Heavy Metal Detox

MSRP: $29.95
You save 33%

$19.95

Heavy metals don’t belong in your body. Metal toxicity can cause health issues. [Digestive, Intestinal]

Product Description

Benefits

  • Binds with and removes heavy metals from the body.
  • Absorbs heavy metal ions.
  • Support the liver.
  • Helps the body replenish vital minerals.

Heavy Metal Detox [Digestive, Intestinal]. Scientists estimate that over 50 percent of U.S. residents have too much heavy metal in their bodies. These metals, which include lead, mercury, aluminum, cadmium and arsenic, are found in industrial byproducts as well as in tainted drinking water, pesticides and even things as common as dental fillings and cooking utensils.

Heavy Metal Detox is a potent detoxification support product designed to bind with and remove heavy metals in the body.

This formula also supports the liver it its efforts to cleanse, detoxify and replenish the body with essential minerals.

The key ingredient, cilantro, appears to decrease the level of heavy metals in the body and increase their levels in the urine.

Recommended Usage:

Take one capsule twice daily with a meal. Do not exceed recommended dose.

If symptoms of headache, nausea, or diarrhea develop, reduce dosage and see your health care practitioner.

SIZE: 90 capsules
STOCK NUMBER: 507-1

Heavy Metal Detox

Don’t Let Heavy Metals Weigh You Down

Scientists estimate that over 50 percent of us. residents have too much heavy metal in their bodies. These metals, which include lead, mercury, aluminum, cadmium and arsenic, are found in industrial byproducts as well as tainted drinking water, pesticides and even things as common as dental fillings and cooking utensils.

Heavy Metal Detox is a potent detoxification support product designed to bind with and remove heavy metals from the body. This formula also supports the liver it its efforts to cleanse, detoxify and replenish the body with essential minerals.

BENEFITS

  • Binds with and removes heavy metals from the body.
  • Absorbs heavy metal ions.
  • Supports the liver.
  • Helps the body replenish vital minerals.

HOW IT WORKS

The ingredients in Heavy Metal Detox, including cilantro, bind with heavy metals so the body can remove them through the urine and bowel. Other ingredients, such as N-Acetyl Cysteine stimulate the detoxification in the liver while kelp algae replaces minerals and nutrients.

NSP ADVANTAGE

NSP Heavy Metal Detox is a unique combination of ingredients specially formulated and balanced to not only support the removal of heavy metals but also to restore the proper levels of vital minerals and nutrients in the body.

SCIENTIFIC SUPPORT

Clinical studies have demonstrated that the ingredients in Heavy Metal Detox bind with heavy metals and remove them from the body. Cilantro, one of the main ingredients in Heavy Metal Detox, has proven particularly effective at supporting the removal of metals through the urine.

INGREDIENTS

Heavy Metal Detox contains cilantro, N-Acetyl Cysteine, apple pectin, sodium alginate, kelp algae, 1- methionine, alpha lipoic acid, magnesium and pyridoxal- 5 -phosphate.

RECOMMENDED USE

Take 1 capsule with a meal twice daily. Do not exceed recommended dose. If headache, nausea or diarrhea develop, reduce dosage and see your health care provider.

Heavy Metal Detox

Heavy metal-induced toxicity resulting from chronic exposure to heavy metals is quickly becoming a serious health problem around the globe. Conservative estimates state that upwards of 25% of the U.S. population (1 out of every 4 Americans) suffer to some degree from heavy metal poisoning. Contamination of the air, soil, water and food supply with heavy metals results in the accumulation of toxic heavy metals in the body. The heavy metals most frequently encountered are aluminum, arsenic, cadmium, lead, mercury and nickel. Even at minute levels, these toxic metals can have detrimental effects on virtually every system of the body, with the integrity of the cardiovascular, gastrointestinal, neurological and urological systems being especially vulnerable to heavy metal-induced impairment. Symptoms of heavy metal toxicity include fatigue, immune system dysfunction, behavior and mood disturbances, musculoskeletal complaints, and gastrointestinal (GI) and neurological problems, as well as anemia, high blood pressure, kidney and liver dysfunction, and endocrine disorders. Fortunately, research shows that a variety of nutritional supplements can help reduce and even inhibit the adverse effects of heavy metals, as well as aid in their elimination from the body.1-3

Heavy Metal Detox is designed to facilitate the elimination of toxic heavy metals from the body, while also protecting cells against the adverse effects of heavy metal exposure. Heavy Metal Detox also supports liver function and healthy elimination in order to minimize reuptake of heavy metals from the bowels. In addition, Heavy Metal Detox contains a blend of ingredients that provide essential vitamins, minerals and nutrients necessary for cellular detoxification and repair. Heavy Metal Detox contains:

Vitamin B6 (pyridoxal-5-phosphate) - Vitamin B6 has been shown to inhibit lead uptake, as well as reduce lead intoxication and cytotoxicity (toxicity to cells) by mobilizing lead deposits in tissues and enhancing its excretion through the urine. In addition, vitamin B6 is a key component in the formation of neurotransmitters such as dopamine and serotonin, and is therefore essential for regulating mood and behavior. Vitamin B6 also increases the bioavailability of magnesium. Deficiency of vitamin B6 leads to impaired immune responses, and has recently been linked to multiple chemical sensitivity (MCS)—vitamin B6 deficiency can cause low taurine levels, which in turn, can result in the development of extreme sensitivities to alcohols, aldehydes, ammonia, chlorine, chlorite (bleach) and solvents. Vitamin B6 is converted into pyridoxal-5-phosphate (PLP), the metabolically active form of vitamin B6, in the liver. PLP is the primary circulating form of vitamin B6 exported from the liver and is considered to be the most relevant diagnostic indicator of functional vitamin B6 status. Research has shown that plasma PLP levels are significantly lower in a majority of patients with impaired liver function, which indicates that a poorly functioning liver may not be able to adequately convert inactive forms of vitamin B6 (such as pyridoxine HCl) into PLP.2,4-8

Cilantro is an herb that has demonstrated an affinity for mercury. Cilantro has been shown to successfully eliminate mercury deposits in internal organs, as well as accelerate the excretion of aluminum, lead and mercury from the body through the urine. In addition, cilantro significantly decreased both lead deposition in the femur and severe lead-induced injury in the kidneys of mice. The researchers concluded that cilantro’s suppressive activity on lead deposition most likely resulted from the chelation of lead by some substances contained in cilantro that are yet unknown. Various nutrients that have been identified in cilantro include beta-carotene, riboflavin, thiamine, niacin, vitamin C, and the minerals calcium, copper, iron, magnesium, manganese, phosphorus and potassium.1,9-12

Sodium alginate, a water-absorbing, gelatinous substance derived from brown seaweed, has been shown to inhibit toxic heavy metal uptake in the bowels. Sodium alginate binds heavy metals and other toxins in the gastrointestinal tract and exerts a bulk laxative action that draws these substances out of the body in the feces. Research indicates that sodium alginate exhibits a high specificity for the binding of radioactive strontium-90, as well as cadmium, lead, mercury and nickel.1,2,12-20

Apple pectin, a source of water-soluble, dietary fiber, helps soften stools and increases bowel transit time, thus minimizing reuptake of heavy metals from the bowels. Fecal elimination is especially important with respect to mercury. Apple pectin binds heavy metals, as well as chemical toxins, in the intestines and expels them from the body. One study has shown that apple pectin exhibits a high affinity for cobalt ions—exposure to cobalt-containing materials may cause lung cancer in humans.1-3,21-23

N-Acetyl-L-cysteine (NAC) appears to have some clinical benefit as a chelating agent in the treatment of acute heavy metal poisoning. NAC has been shown to promote the elimination of toxic metals, as well as protect the liver and kidneys against damage from proinflammatory immune factors that are released by the liver in response to heavy metal exposure. In particular, NAC has been used to effectively reduce the body burden of mercury. In fact, oral administration of NAC produced a profound acceleration of urinary methylmercury excretion in mice compared to the control group. Methylmercury is a ubiquitous (being everywhere) environmental pollutant and potent neurotoxin. Furthermore, NAC has also been shown to protect animals from asbestos-induced oxidative damage and the resulting depletion of glutathione (the most important antioxidant for liver detoxification) levels. Asbestos is an extremely toxic and carcinogenic substance.3,24-29

Magnesium (citrate) - Magnesium protects against heavy metal-induced toxicity and has been shown to be a competitive antagonist (a substance that blocks or nullifies the actions of another) of the toxicological effects of nickel. However, a deficiency of magnesium can actually increase heavy metal toxicity. Many heavy metal-burdened individuals exhibit increased urinary magnesium excretion, and there appears to be an association between magnesium deficiency and increased sensitivity in patients with multiple chemical sensitivity (MCS). In addition, low dietary magnesium, coupled with calcium deficiency, may contribute to aluminum-induced degenerative nervous disease. Furthermore, magnesium deficiency results in decreased amounts of cytochrome P450, which is essential to the proper functioning of phase I detoxification—one of 2 distinct phases of detoxification that takes place in the liver, by which toxins are chemically transformed into progressively more water-soluble substances that can be more readily excreted. Magnesium citrate has been shown to be more soluble and more bioavailable, with respects to gastrointestinal absorbability, than magnesium oxide.1-3,30-33

l-Methionine, a sulfur-containing amino acid, acts as a powerful detoxifier of heavy metals, including lead and cadmium. Methionine also demonstrates antioxidant properties and protective effects against alcohol. Elimination of fat-soluble compounds, particularly heavy metals like lead and mercury, requires adequate levels of glutathione, which in turn requires sufficient levels of methionine—an essential component for glutathione synthesis. As levels of toxic compounds in the body increase, more methionine is utilized for glutathione synthesis. Researchers attribute much of the beneficial effect of methionine on heavy metal toxicity to its ability to increase the bioavailability of glutathione. Methionine deficiency negatively impacts detoxification by reducing hepatic (liver) and intestinal mixed function oxidase (MFO) enzyme activity. Low methionine intake also hampers selenium metabolism—selenium reduces the toxicity of lead and facilitates the excretion of cadmium and mercury from the liver. Adequate supplementation of vitamin B6 is necessary when supplementing with methionine.1,2,34-38

Kelp contains algin, a non-digestible dietary fiber that binds heavy metals and radioactive particles in the intestines and draws these substances out of the body. Kelp also contains fucoidan, a polysaccharide that has demonstrated inhibitory effects on the absorption of heavy metals. Animal and in vitro research shows that fucoidan exhibits antiproliferative and antitumor activity, with preliminary results indicating that fucoidan may serve as a potent antitumor agent in cancer therapy. From a nutritional standpoint, kelp provides a high concentration of minerals (calcium, magnesium, iodine, iron and potassium), vitamins, essential amino acids, protein, and dietary fiber. In fact, research indicates that algal dietary fiber may provide important functional activities, including antioxidant, anticoagulant, antimutagenic and antitumor effects, as well as the ability to alter lipid (fat) metabolism.14,16,39-43

Alpha lipoic acid (ALA) has been shown to protect cells against heavy metal-induced toxicity. Animal research has demonstrated that ALA significantly decreases cadmium-induced liver damage, while both in vitro and in vivo studies have found ALA to be effective in chelating mercury from renal (kidney) tissue. ALA also dramatically enhanced biliary (gallbladder) excretion of inorganic mercury in rats. Furthermore, ALA has been shown to be highly effective in reducing lead-induced oxidative stress, and significantly increased the survival of lead-exposed hamster ovary cells in vitro, suggesting that ALA may be beneficial in the therapeutic intervention of lead poisoning.44-50

References:

1Bock MD, S. “Diagnosis and Treatment of Heavy Metal Toxicity.” International Journal of Integrative Medicine; 1999, 1(6):7-12.

2Pizzorno, J. & Murray, M. Textbook of Natural Medicine, 2nd ed. London: Churchill Livingstone, 1999.

3Crinnion ND, W.J. “Environmental Medicine, Part Three: Long-Term Effects of Chronic Low-Dose Mercury Exposure.” Alternative Medicine Review; 2000, 5(3):209-223.

4Tandon, S.K., et. al. “Chelation in metal intoxication. XXIV: Influence of various components of vitamin B complex on the therapeutic efficacy of disodium calcium versenate in lead intoxication.” Pharmacology & Toxicology; 1987, 60(1):62-65.

5Fischer AB, et. al. “Testing of chelating agents and vitamins against lead toxicity using mammalian cell cultures.” Analyst; 1998, 123(1):55-58.

6Lininger Jr, S., et. al. The Natural Pharmacy, 2nd Ed. Rocklin, CA: Prima Publishing, 1999.

7Trakatellis, A., et. al. “Pyridoxine deficiency: new approaches in immunosuppression and chemotherapy.” Postgraduate Medical Journal; 1997,73(864):617-622.

8“Vitamin B6 (Pyridoxine; Pyridoxal 5’-Phosphate).” Alternative Medicine Review; 2001, 6(1):87-92.

9Omura, Y., et. al. “Significant mercury deposits in internal organs following the removal of dental amalgam, & development of pre-cancer on the gingiva and the sides of the tongue and their represented organs as a result of inadvertent exposure to strong curing light (used to solidify synthetic dental filling material) & effective treatment: a clinical case report, along with organ representation areas for each tooth.” Acupuncture & Electrotherapeutics Research; 1996, 21(2):133-160.

10—. “Role of mercury (Hg) in resistant infections & effective treatment of Chlamydia trachomatis and Herpes family viral infections (and potential treatment for cancer) by removing localized Hg deposits with Chinese parsley and delivering effective antibiotics using various drug uptake enhancement methods.” Acupuncture & Electrotherapeutics Research; 1995, 20(3-4):195-229.

11Aga, M., et. al. “Preventive effect of Coriandrum sativum (Chinese parsley) on localized lead deposition in ICR mice.” Journal of Ethnopharmacology; 2001, 77(2-3):203-208.

12Duke PhD, J. “Dr. Duke’s Phytochemical and Ethnobotanical Databases.” http://www.ars-grin.gov/duke/plants.html.

13Rose, H.E. & Quarterman, J. “Dietary fibers and heavy metal retention in the rat.” Environmental Research; 1987, 42(1):166-175.

14Stansbury ND, J. “Cancer Prevention Diet.” Nutrition Science News; August 1999.

15Newall, C., et. al. Herbal Medicines. London, England: The Pharmaceutical Press, 1996.

16Fremerman, S. “Kelp.” Natural Health; 1999; 29(9):42.

17Gong, Y.F., et. al. “Suppression of radioactive strontium absorption by sodium alginate in animals and human subjects.” Biomedical and Environmental Sciences; 1991, 4(3):273-282.

18Seki, H. & Suzuki, A. “Biosorption of Heavy Metal Ions to Brown Algae, Macrocystis pyrifera, Kjellmaniella crassiforia, and Undaria pinnatifida.” Journal of Colloid and Interface Science; 1998, 206(1):297-301.

19Mowrey PhD, D. The Scientific Validation of Herbal Medicine. New Canaan, CT: Keats Publ., 1986.

20Lazaro, N., et. al. “Heavy metal biosorption by gellan gum gel beads.” Water Research; 2003, 37(9):2118-2126.

21Fitzgerald, F. “Detoxify for better health.” Nature’s Impact; April/May, 1998.

22Kartel, M.T., et. al. “Evaluation of pectin binding of heavy metal ions in aqueous solutions.” Chemosphere; 1999, 38(11):2591-2596.

23Bucher, J.R., et. al. “Inhalation toxicity and carcinogenicity studies of cobalt sulfate.” Toxicological Sciences; 1999, 49(1):56-67.

24Kelly ND, G.S. “Clinical Applications of N-Acetylcysteine.” Alternative Medicine Review; 1998, 3(2):114-127.

25Patrick ND, L. “Nutrients and HIV: Part Three—N-Acetylcysteine, Alpha-Lipoic Acid, L-Glutamine, and L-Carnitine.” Alternative Medicine Review; 2000, 5(4):290-305.

26Dong, W., et al. “Toxic metals stimulate inflammatory cytokines in hepatocytes through oxidative stress mechanisms.” Toxicology and Applied Pharmacology; 1998, 151(2):359-366.

27Sterling RD, M. “Can Cirrhosis Be Prevented?” Nutrition Science News; January 1999.

28Ballatori N, et. al. “N-acetylcysteine as an antidote in methylmercury poisoning.” Environonmental Health Perspectives; 1998, 106(5):267-271.

29Head ND, K. “Protecting Your Patients After Asbestos Exposure.” Alternative Medicine Review; 2001, 6(5).

30Hass, B.S., et. al. “Actions and interactions of nickel and magnesium on the transformation response of transformed cells in culture.” Annals of Clinical and Laboratory Science; 1996, 26(1):18-30.

31Littlefield NA, et. al. “Hydroxylation and deglycosylation of 2'-deoxyguanosine in the presence of magnesium and nickel.” Chemico-Biological Interactions; 1991; 79(2):217-228.

32Goyer, R.A. “Toxic and essential metal interactions.” Annual Review of Nutrition; 1997, 17:37-50.

33Lindberg, J.S., et. al. “Magnesium bioavailability from magnesium citrate and magnesium oxide.” Journal of the American College of Nutrition; 1990, 9(1):48-55.

34Kachru, D.N., et. al. “Influence of methionine supplementation in chelation of lead in rats.” Biomedical and Environmental Sciences; 1989, 2(3):265-270.

35Gubrelay, U., et. al. “Effects of thiamin and methionine administration in preventing cadmium-induced biochemical alterations and metal concentration in male rats.” Journal of Trace Elements in Medicine and Biology; 1998, 12(2):86-90.

36Chaitow ND, L. Thorsons Guide to Amino Acids. London: Thorsons, 1991.

37Parcell, S. “Sulfur in Human Nutrition and Applications in Medicine.” Alternative Medicine Review; 2002, 7(1):22-44.

38Wang, S.T., et. al. “Methionine and cysteine affect glutathione level, glutathione-related enzyme activities and the expression of glutathione S-transferase isozymes in rat hepatocytes.” Journal of Nutrition; 1997, 127(11):2135-2141.

39Lee PhD, W. Kelp, Dulse and Other Sea Supplements. New Canaan, CT: Keats, 1983.

40Becker, G., et. al. Influence of fucoidan on the intestinal absorption of iron, cobalt, manganese and zinc in rats.” Digestion; 1981, 21(1):6-12.

41Teas, J., et. al. “Dietary seaweed (Laminaria) and mammary carcinogenesis in rats.” Cancer Research; 1984, 44(7):2758-2761.

42Riou, D., et. al. “Antitumor and antiproliferative effects of a fucan extracted from ascophyllum nodosum against a non-small-cell bronchopulmonary carcinoma line.” Anticancer Research; 1996, 16(3A):1213-1218.

43Jimenez-Escrig, A. & Goni Cambrodon, I. “[Nutritional evaluation and physiological effects of edible seaweeds].” Archivos Latinoamericanos de Nutrición; 1999, 49(2):114-120.

44Nichols Jr MD, T.W. “a-Lipoic Acid: Biological Effects and Clinical Implications.” Alternative Medicine Review; 1997, 2(3):177-183.

45Ramakrishnan, N., et. al. “Radioprotection of hematopoietic tissues in mice by lipoic acid.” Radiation Research; 1992, 130(3):360-365.

46Sumathi, R., et. al. “Relationship between glutathione and DL alpha-lipoic acid against cadmium-induced hepatotoxicity.” Japanese Journal of Medical Science & Biology; 1996, 49(2):39-48.

47Keith, R.L., et. al. “Utilization of renal slices to evaluate the efficacy of chelating agents for removing mercury from the kidney.” Toxicology; 1997, 15;116(1-3):67-75.

48Gregus, Z., et. al. “Effect of lipoic acid on biliary excretion of glutathione and metals.” Toxicology and Applied Pharmacology; 1992, 114(1):88-96.

49Pande, M. & Flora, S.J. “Lead induced oxidative damage and its response to combined administration of alpha-lipoic acid and succimers in rats.” Toxicology; 2002, 15;177(2-3):187-196.

50Gurer, H., et. al. “Antioxidant role of alpha-lipoic acid in lead toxicity.” Free Radical Biology & Medicine; 1999, 27(1-2):75-81.

Additional Information

Size:

90 capsules

Kosher:

No

UPC:

099904005075

Stock Number:

507

Body System:

Digestive, Intestinal

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